Free Essays on Groups And Teams

Groups and Teams In this age of rapidly changing technology, market-driven decision making, customer sophistication, and employee restlessness, leaders and managers are faced with new challenges. Organizations must build new structures and master new skills in order to compete and survive. As work settings become more complex and involve increased numbers of interpersonal interactions, individual effort has less impact. In order to increase efficiency and effectiveness of high performance, a group effort is required. The creation of teams has become a key strategy in many organizations. Team building is an essential element in supporting and improving the effectiveness of small groups and task forces and must be a key part of a total program of organizational change. This paper discusses the characteristics of high performance teams and how a group can become a high performance team. Included is an examination of the impact of demographic and cultural diversity on group behavior. Diversity in culture and demographic characteristics can be a source of friction and conflict or be one of the team's greatest strengths. A group can become a high-performing team by understanding how cultural and demographic dissimilarity influences group behavior. High-performing teams leverage their diversity for competitive advantage. Firstly, let us examine the definition of teams and high performances and the link between those two. A team is a small group of people with complementary skills, who work actively together to achieve a common purpose for which they hold themselves collectively accountable (Schermerhorn, 2003, Ch. 10). The high performance team is the unit of effectiveness for the high performance enterprise. Relevant topics include kick starting a brand new team, the intensity and focus of 'hot groups,' team building success strategies, and team process management. High performance teams are otherwise known as self-managed groups or sel... Free Essays on Groups And Teams Free Essays on Groups And Teams Groups and Teams In this age of rapidly changing technology, market-driven decision making, customer sophistication, and employee restlessness, leaders and managers are faced with new challenges. Organizations must build new structures and master new skills in order to compete and survive. As work settings become more complex and involve increased numbers of interpersonal interactions, individual effort has less impact. In order to increase efficiency and effectiveness of high performance, a group effort is required. The creation of teams has become a key strategy in many organizations. Team building is an essential element in supporting and improving the effectiveness of small groups and task forces and must be a key part of a total program of organizational change. This paper discusses the characteristics of high performance teams and how a group can become a high performance team. Included is an examination of the impact of demographic and cultural diversity on group behavior. Diversity in culture and demographic characteristics can be a source of friction and conflict or be one of the team's greatest strengths. A group can become a high-performing team by understanding how cultural and demographic dissimilarity influences group behavior. High-performing teams leverage their diversity for competitive advantage. Firstly, let us examine the definition of teams and high performances and the link between those two. A team is a small group of people with complementary skills, who work actively together to achieve a common purpose for which they hold themselves collectively accountable (Schermerhorn, 2003, Ch. 10). The high performance team is the unit of effectiveness for the high performance enterprise. Relevant topics include kick starting a brand new team, the intensity and focus of 'hot groups,' team building success strategies, and team process management. High performance teams are otherwise known as self-managed groups or sel...

Free Essays on Groups And Teams

Groups and Teams In this age of rapidly changing technology, market-driven decision making, customer sophistication, and employee restlessness, leaders and managers are faced with new challenges. Organizations must build new structures and master new skills in order to compete and survive. As work settings become more complex and involve increased numbers of interpersonal interactions, individual effort has less impact. In order to increase efficiency and effectiveness of high performance, a group effort is required. The creation of teams has become a key strategy in many organizations. Team building is an essential element in supporting and improving the effectiveness of small groups and task forces and must be a key part of a total program of organizational change. This paper discusses the characteristics of high performance teams and how a group can become a high performance team. Included is an examination of the impact of demographic and cultural diversity on group behavior. Diversity in culture and demographic characteristics can be a source of friction and conflict or be one of the team's greatest strengths. A group can become a high-performing team by understanding how cultural and demographic dissimilarity influences group behavior. High-performing teams leverage their diversity for competitive advantage. Firstly, let us examine the definition of teams and high performances and the link between those two. A team is a small group of people with complementary skills, who work actively together to achieve a common purpose for which they hold themselves collectively accountable (Schermerhorn, 2003, Ch. 10). The high performance team is the unit of effectiveness for the high performance enterprise. Relevant topics include kick starting a brand new team, the intensity and focus of 'hot groups,' team building success strategies, and team process management. High performance teams are otherwise known as self-managed groups or sel... Free Essays on Groups And Teams Free Essays on Groups And Teams Groups and Teams In this age of rapidly changing technology, market-driven decision making, customer sophistication, and employee restlessness, leaders and managers are faced with new challenges. Organizations must build new structures and master new skills in order to compete and survive. As work settings become more complex and involve increased numbers of interpersonal interactions, individual effort has less impact. In order to increase efficiency and effectiveness of high performance, a group effort is required. The creation of teams has become a key strategy in many organizations. Team building is an essential element in supporting and improving the effectiveness of small groups and task forces and must be a key part of a total program of organizational change. This paper discusses the characteristics of high performance teams and how a group can become a high performance team. Included is an examination of the impact of demographic and cultural diversity on group behavior. Diversity in culture and demographic characteristics can be a source of friction and conflict or be one of the team's greatest strengths. A group can become a high-performing team by understanding how cultural and demographic dissimilarity influences group behavior. High-performing teams leverage their diversity for competitive advantage. Firstly, let us examine the definition of teams and high performances and the link between those two. A team is a small group of people with complementary skills, who work actively together to achieve a common purpose for which they hold themselves collectively accountable (Schermerhorn, 2003, Ch. 10). The high performance team is the unit of effectiveness for the high performance enterprise. Relevant topics include kick starting a brand new team, the intensity and focus of 'hot groups,' team building success strategies, and team process management. High performance teams are otherwise known as self-managed groups or sel...

Free Essays on Groups And Teams

Groups and Teams In this age of rapidly changing technology, market-driven decision making, customer sophistication, and employee restlessness, leaders and managers are faced with new challenges. Organizations must build new structures and master new skills in order to compete and survive. As work settings become more complex and involve increased numbers of interpersonal interactions, individual effort has less impact. In order to increase efficiency and effectiveness of high performance, a group effort is required. The creation of teams has become a key strategy in many organizations. Team building is an essential element in supporting and improving the effectiveness of small groups and task forces and must be a key part of a total program of organizational change. This paper discusses the characteristics of high performance teams and how a group can become a high performance team. Included is an examination of the impact of demographic and cultural diversity on group behavior. Diversity in culture and demographic characteristics can be a source of friction and conflict or be one of the team's greatest strengths. A group can become a high-performing team by understanding how cultural and demographic dissimilarity influences group behavior. High-performing teams leverage their diversity for competitive advantage. Firstly, let us examine the definition of teams and high performances and the link between those two. A team is a small group of people with complementary skills, who work actively together to achieve a common purpose for which they hold themselves collectively accountable (Schermerhorn, 2003, Ch. 10). The high performance team is the unit of effectiveness for the high performance enterprise. Relevant topics include kick starting a brand new team, the intensity and focus of 'hot groups,' team building success strategies, and team process management. High performance teams are otherwise known as self-managed groups or sel... Free Essays on Groups And Teams Free Essays on Groups And Teams Groups and Teams In this age of rapidly changing technology, market-driven decision making, customer sophistication, and employee restlessness, leaders and managers are faced with new challenges. Organizations must build new structures and master new skills in order to compete and survive. As work settings become more complex and involve increased numbers of interpersonal interactions, individual effort has less impact. In order to increase efficiency and effectiveness of high performance, a group effort is required. The creation of teams has become a key strategy in many organizations. Team building is an essential element in supporting and improving the effectiveness of small groups and task forces and must be a key part of a total program of organizational change. This paper discusses the characteristics of high performance teams and how a group can become a high performance team. Included is an examination of the impact of demographic and cultural diversity on group behavior. Diversity in culture and demographic characteristics can be a source of friction and conflict or be one of the team's greatest strengths. A group can become a high-performing team by understanding how cultural and demographic dissimilarity influences group behavior. High-performing teams leverage their diversity for competitive advantage. Firstly, let us examine the definition of teams and high performances and the link between those two. A team is a small group of people with complementary skills, who work actively together to achieve a common purpose for which they hold themselves collectively accountable (Schermerhorn, 2003, Ch. 10). The high performance team is the unit of effectiveness for the high performance enterprise. Relevant topics include kick starting a brand new team, the intensity and focus of 'hot groups,' team building success strategies, and team process management. High performance teams are otherwise known as self-managed groups or sel...

Strategies for writing an ideal teacher resume -TheJobNetwork

Strategies for writing an ideal teacher resume -TheJobNetwork If you’re a teacher (or working on becoming one), you know that by the time you complete your degree(s), your training courses, and any standardized exams your state throws your way, the job search can feel like yet another daunting process. Or maybe you’re further along in your career and you’re ready for a scenery change, or a subject change. Whatever the case may be, your resume should be a painless part of the process. Let’s look at some strategies you can use as you craft your own teaching resume. Do a little pre-resume brainstorming.Before you start cranking away, here are some resume basics to consider before you even start working on your resume. Ask yourself:Who is going to be reading this? Will it be another educator or administrator, or a layperson? This can help you determine how much jargon or career shorthand you can use.What do I want to emphasize most about myself and my career? What are the assets that make you the most valuable hire?What is my goal with this resume? Are you looking to find your first job in the field, change jobs, or move up?Thinking about these things ahead of time helps you refine your resume before you’ve even begun. You’ve got ideas. Now you just need some structure for them†¦Open strong with a headline, objective, or summary.At the top of your resume will be your contact info, of course (don’t be that guy or gal who thinks that the cover email is enough contact info for this digital day and age), but after that is your opening statement. You could just dive right into the details of your resume, but think about it- this is a chance to really introduce yourself to the reader, and set the narrative for the rest of your resume. Chances are, whoever is reading your resume will also be reading a pile of resumes from other people who may be similarly qualified for the job. So you want to take every edge you can get, including a sentence or two to help set you apart from thos e others.Headlines are exactly what they sound like: a brief, bold one-liner about who you are. A headline is brief, and it doesn’t contain your life story, but it does tell the reader who they’re about to meet in the rest of the resume. Here are some examples:Columbus School District Teacher of the Year  Seasoned Educator and Expert Curriculum Builder  Creative, Metrics-Focused Elementary School Educator Objective statements are a couple of brief sentences letting the reader know your intent. The reader already knows you want a job, so you don’t need to be that explicit. The objective can be more about your short-term goals with this position. Are you looking to change your career? Start your career? Level up with a leadership role? The objective helps the reader see what you’re angling for, besides an interview. Here are some examples:Educator with 10 years of experience seeking an administrative role.Looking for a position as a special-needs teache r at Washington Academy, bringing a creative, high-energy approach to student outcomes.Seeking a position as a math teacher focusing on technology integration and curriculum best practices to improve student achievement.Summary statements are more of a brief collection of highlights that you want to emphasize about yourself. Resume summaries are sometimes called â€Å"qualifications summaries† or â€Å"competencies.† Here, you call out the skills and accomplishments that you want the reader to focus on. For example:Motivated, energetic teacher who values diversity and creativity in the classroomResults-focused leader with a record of improving student test scores year-over-year15 years of curriculum-building experience, and development of classroom activities in accordance with state standards and best practicesAgain, not the life story, but a bit of a sneak preview for the reader. You should be prepared to back up your intro statements with more detailed skills or exp erience bullets later in the resume.Make your experience work for you.As a teacher, you’ve got a lot of things already working for you on your resume: your education and certifications, which are essential elements. Those are concrete points that you don’t really need to finesse or wordsmith- they are what they are. You should highlight your education and credentials in a brief section near the top of the resume.After that, you can start being a little more creative with your resume structure. If you already have a ton of classroom experience, then you can go the traditional route and put your work experience next, followed by skills.If you’re a recent grad or a career changer, and don’t yet have tons of experience, consider going with a more skills-heavy format. This puts your skills and general qualifications front and center, giving it higher priority over the â€Å"experience† section. And even if you feel like you don’t have a lot of ex perience (yet), you do have things you can use to flesh out that experience section. Volunteer work, club or professional association activities, or extracurricular teaching work you’ve done can also be used here. That community writing seminar you ran at the senior center last year? Include it. Your three recent summers as a camp counselor working with elementary age students while you completed your undergrad work? Include it, if it applies to the teaching job you’re seeking. (If you’re seeking an early childhood education job, great- if you’re looking to teach calculus to seniors, maybe not as relevant). You can be creative here to fill in gaps.As you’re building your experience section, don’t forget to list accomplishments, not duties. The person reading the resume is more interested in what you’ve achieved in your career so far, not necessarily what your 10 daily duties were in your last job. It’s important to highlight on ly the most relevant experience points, related to the job you’re seeking.Be selective about your skills.Sure, you may have the highest Candy Crush score in the county, or play the harmonica intro to â€Å"Piano Man† so beautifully it’d make Billy Joel himself cry. Those are great skills to have. But they may not work on your resume. Your skills section, like the rest of your resume, should be laser-focused on the job at hand. These six skill sets are among the top skills for teachers, so you should concentrate on these areas:Communication skills. Teachers communicate all the time- they work directly with students, other teachers, administrators, staff, and parents on a regular basis. Make sure you emphasize your strengths when it comes to writing, speaking, presenting, and- perhaps most importantly- listening.Problem solving skills. Teachers are problem-solvers, and help others solve them as well. You can provide examples of how you solve conflicts, how you can adapt lesson plans in real time, and how you approach those unexpected moments in any classroom.Organizational skills. Hiring managers will be interested to know how you juggle a teacher’s many tasks (classroom teaching, meetings, grading, lesson planning, etc.). Your time management skills are crucial, so definitely emphasize those on your resume.Patience. Whether you’re teaching a classroom of six-year-olds or sixty-year-olds, one of the key characteristics of an educator is patience, and the ability to work with any student to help them learn and achieve. Not everyone has patience, so this is a good skill to include on your resume.People skills. Similarly, general people skills are an asset on your resume. The reader will want to know you can work with others in a productive way, especially students. But this applies to others as well, because teachers are very much team players, interacting with their colleagues and administrators every day as well.Technological s kills. We live in an ever-more-digital world, and teachers who can help bring technology into the classroom productively can be major assets for a school. The skills section is a good place to call out your career-relevant tech expertise.Don’t skip the editing.After you’ve written your resume, there is one more non-negotiable step: you need to review it carefully. Do you really need everything you’ve included? Is everything relevant to the job description? And most important, have you obsessively proofread it, and/or had someone trusted do it for you? It can be tempting to hit â€Å"send† as soon as you write the last word, but you should always, always take that extra step and make sure the whole document is exactly as it should be.For examples of teacher resumes (entry level, mid-career, and seeking upward movement), we’ve got you covered: How to Write a Perfect Teaching Resume (Examples Included). And if you need more inspiration, our Resume Lib rary is a click away as well.

Ottomans Essay Example | Topics and Well Written Essays - 1500 words

Ottomans - Essay Example The Turks conquered the Byzantine city Bilecik in the year 1299. Subsequently, several other cities, villages and forts in Byzantium were conquered by these warriors. These developments took place, in the earlier years of the 1300s. In addition, several of the Turkish principalities and tribes were also annexed (Parry 65). As such, the origin of the Ottoman dates back to the year 1299, when it evolved from a frontier principality of Anatolia. In the years that followed, it emerged as an important empire of the world. Its territory extended from Eastern Europe and the Arabian Peninsula to North Africa, in the sixteenth century. Thereafter, it underwent a gradual decline and was extinguished in the year 1922 (Gocek 3). This was due to the formation of Turkey on its central lands. The merging of western influences with the extant social structure resulted in a divided bourgeois. This brought about fragmentation of its bureaucratic and commercial classes, which in turn resulted in the decline of the Ottoman Empire (Gocek 3).Kosovo was under the control of Serbia for different spells of varying duration, until a final defeat in the year 1455. Thereafter, both these nations became Turkish allies and part of the Ottoman Empire (What is History of Kosovo). Subsequently, Bayezid II became the Ottoman Sultan in the year 1481. He continued in his father’s footsteps, by promoting both eastern and western culture. This was in distinct contradiction to the practices of the other Sultans. In addition, Bayezid II spared no pains in his efforts to have a smooth political culture in the nation. This earned him the well – deserved sobriquet of the Just (Bayezid II). The empire of the Seljuk Turks was undergoing a systematic breakdown. The outcome was the emergence of several Turkish states in Asia Minor. The Ottoman state had its humble beginnings in

The population dynamics of the grizzly bears Literature Review Essay

The population dynamics of the grizzly bears Literature Review - Essay Example Although the population of each group can fluctuate through death and birth rates, with their own probability of going extinct, these groups can also be supported by other groups through occasional contact. The dynamics of these groups are different not only because their living environments and landscapes are not always equally suitable, but also because of their proximity, or lack of it, to other groups. Limited contact with other groups can force one of these smaller groups to become extinct, leading to the collapse of the entire species if too many groups die out. There are several different ways in which a metapopulation might be organized though, not all fitting this classic definition. For instance, the group could have a core group, from which several subgroups branch off and / or rejoin later. There are also situations in which all members of a species exist in small patches that remain more closely entwined with each other, saving each other from extinction and freely passi ng members from one patch or subgroup to another. There are also situations in which subgroups are sparsely distributed over adequate environments to such an extent that they have no capacity to reach each other and some appropriate living areas remain void of this species.

Virus-host Receptor Interactions in Biology

Virus-host Receptor Interactions in Biology Abstract Viruses are obligate intracellular parasites and, as such, must penetrate a suitable host cell in order to replicate their genomes and disseminate. Most viruses are limited to a specific set of cells or tissues in which they can successfully replicate, and this may be in one or more particular species. When viruses are able to bind a variety of cells, the pathogenesis and overall effect on the organism may differ. The main determinants of viral tropism differ between different virus families, but in order to take the first, and arguably most important step, in the infection of a host cell, the virus must attach via specific interactions between cell surface molecules and viral proteins. Enveloped viruses usually have proteins embedded in their envelope, assembled at the host cell surface prior to budding. In the case of some viruses (such as HIV-1), these may even consist of cellular proteins from the host cell itself. Non- enveloped viruses are usually internalized in some way and uncoated in an endosome in a pH-dependant manner. Many viruses require a number of cell surface receptors for cell entry, and it is this combination, added to other factors such as replication proteins, that determine whether or not a virus can penetrate and replicated within a certain cell. Introduction As obligate intracellular parasites, the life cycle of viruses depends on an intracellular replication phase and they are thus dependant on living cells. The first essential interaction a virus makes with a host cell is with a cell-surface receptor. A viral receptor may be defined as any cell surface component that mediates recognition of a cell and facilitates entry of the virus and subsequent infection. Receptors serve to ensure infection by overcoming repulsion between the virus and cell. (Baranowski, Flint, Jindrak, modern virol) Cellular receptors are generally proteins, although other types of receptor, such as carbohydrates, may be used (see table 1). These molecules are essential components of the cell or extracellular matrix and functions may include cell adhesion, signalling e.g. chemokine and growth factor receptors. (Baranowski 2003) While some viruses require only one receptor, binding to one cellular receptor alone may not be sufficient for initiation of infection for other viruses. Viruses may bind two or more receptors in sequence in order to initiate endocytosis or membrane fusion. For some viruses, the first contact with a cell is through a low-affinity interaction with a ubiquitous molecule, which allows the primary receptor-virus interaction to take place. The primary receptor is generally unique to certain cells and therefore partly defines the tropism of that particular virus, as cells are rendered susceptible to infection by a certain virus if the receptor required for attachment and entry is present. The primary attachment receptor may induce a conformational change in the viral envelope protein bound, to induce further interaction with the cell. (Modern Virology) A further interaction may then be required to initiate infection, performed by a coreceptor.The definition of the term coreceptor may sometimes be ambiguous, but generally, it is taken to be the molecule that induces fusion or penetration of a cell. This may be a further determinant of tropism, for example the interaction of HIV-1 Virus entry into a cell is the first step in the life0cycle of a virus; various mechanisms of viral cell enrty are shown in figure 1. The mechanism of entry varies between viruses, but all begin with the binding of a cellular receptor by a viral protein. Binding of a cellular receptor may induce endocytosis or formation of an endosome, the acidic environment of which induces uncoating; this may be dependent upon cellular proteins clathrin or caveolin. Enveloped viruses may require an acidic environment that will induce conformational changes in envelope proteins required to induce membrane fusion, while others, including the measles and HIV viruses, can fuse directly with the plasma membrane at neutral pH. (Baranowski) Fusion at the plasma membrane releases the nucelocapsid into the cytoplasm, where the virus can make its way to the nucleus or begin replication in the cytoplasm. The differences in these entry pathways are due to the nature of the molecular interactions between the vi ral components and target-cell receptors, for example, viruses that mimic the natural ligand of receptors for signalling molecules interefere with their signalling to promote viral entry into the cell and spread of infection. (Bomsell) Conformational changes resulting from the binding of a primary receptor that allow the binding of a fusion receptor are a common mechanism among various types of virus, including influenza and HIV type 1, examples and brief description. Similar to Influenza . Multiple receptors could be coreceptors and act together either to modulate each other or to contribute complementary functions. Alternatively, the receptors might act sequentially. Binding of the virus to the first receptor could cause changes in the virus or host that are necessary before the second receptor can bind (50). For those viruses in fluids with flow, such as blood or respiratory secretions, the initial binding must be able to effect rapid docking of the virus to its host cell. (Haywood) As previously stated, some viruses recognise more than one cellular receptor. The same receptor may also be used by more than one type of virus. (see table 1) Often, these are highly abundant in many tissues, for example, heparan sulfate can serve as a receptor for many viruses, including Human immunodefiecieny virus, Hepatitis C and Dengue Virus and as a co-receptor for Herpesviruses (excluding EBV). (ODonnel) CAR, acts as a receptor for both coxsackie and adenoviruses. (Schneider) Table 1 illustrates the diversity of cell surface molecules which viruses have adapted to recognise. Some viruses use more than one type of molecule as a primary receptor e.g. reoviruses bind to the beta-adrenergic receptor as well as NAN. (Flint) While the presence of certain receptors on host cells is vital to initiate infection, these interactions are not always sufficient to explain all aspects of cell, tissue and species tropism. (Flint)(Haywood, Schneider) Binding of a viral protein to a cell surface receptor does not necessarily mean a productive infection will follow, since a co-receptor may be absent or functional domains of the receptor may be blocked. (Baranowski) Absence of specific cytoplasmic or nuclear molecules may hinder the replication of some viruses, despite their permissivity. However, even a non-productive infection may induce pathogenic effects, for example, binding to specific receptor may induce the secretion of cytokines. (Schneider) A virus generally cannot infect a cell successfully in the absence of its specific receptor, so the distribution around the body of the receptor will act as a restriction on the range of tissues that can be infected and hence on the number of systems in the body where sig ns and symptoms of infection might be experienced. (Flint) In the true sense of the word, Tropism refers to the specific cells a particular virus is able to replicate in, although the use of receptor by a virus is increasingly a valid definition in the field of virology. Additional factors the cause viral tropism will not be considered in the context of this essay, although they may be mentioned briefly where relevant, since the focus of this review is the link between specific receptor usage and virus tropism and pathogenesis. (Kuhmann) The primary topics explored here are the virus-receptor interactions with cells that allow viruses to enter cells and initiate infection and how this relates to the tropism of the virus at a cellular and organismal level. I am to demonstrate how viral attachment and entry is often a complicated multi-step process, sometimes requiring many different cell and virus molecules. The viruses largely used to illustrate these points, Human Immunodeficiency Virus type 1 (HIV-1), Influenza A and Herpes Simplex Virus type 1 (HSV-1) are human viruses of medical significance, but the tropism of these particular viruses in other animals, along with other viruses specific to other animals will be discussed where relevant. The structure and genomic organisation of these viruses is irrelevant and is only discussed where it relates to the glycoproteins that interact with cellular receptors. Viruses of plants, fungi and bacteria are not discussed The presence on the cell surface of a protein that has been identified as the receptor for a given virus may not be sufficient for a productive viral infection, and there may be multiple mechanisms behind such restrictions: functional domains of the receptor may be blocked in some cellular context, additional proteins (or other cofactors) may be needed, or cells may exhibit impediments for completion of the infection cycle, despite an initial successful interaction with a functional receptor. HSV- Demonstrates how viruses may use a large number of viral proteins and receptors to bind and enter specific cells. (Hayashi and Yoon) and how the interactions are a complex multi-step process. Influenza multiple steps. binds many cell types Tropism is dependent on other receptors and interactions. Of the many examples, the interaction of  the human influenza A virus hemagglutinin  with N-acetylneuraminic acid, and the ensuing  conformational alterations involved  in pH-dependent membrane fusion, are one  of the best characterized at the structural  and functional levels (11) (Baranowski 2001)  example of proteolytic cleavage to aid spread and pathogenesis. Conformational change required for fusion HIV A well-documented case of use of multiple receptos is that of HIV-1 viruses and related viruses. Illustrates how a virus may use multiple coreceptors to mediate entry to different types of cells and thus influence the tropism of this virus. Uses some of the same receptors as other viruses (parallels between HIV, HSV and influenza) Multi-step process The interaction of the virion with the attachment receptor leads to the first conformational changes in the envelope proteins. This step enables the interaction with co-receptors, or entry mediators and further conformational changes at the plasma membrane. In enveloped viruses (top), this may deliver the energy for the direct fusion of the viral envelope and cellular membrane. Some enveloped and non-enveloped viruses require the low pH in acidic endosomes to induce this conformational change. Enveloped viruses may require the low pH to induce membrane fusion (centre). These mechanisms lead to the release and possibly uncoating of the virus genome, and the initiation of the virus replication cycle. Role of Viral Receptor Destruction While non-enveloped viruses typically undergo relase through cytolysis. Influenza and HIV-1 Viruses also demonstrate the importance of receptor-destroying activity on the infectivity of some viruses. This is imperative for the efficient release and cell-cell spread of the virus by preventing the glycoproteins on the newly-emerged virus from binding to the host cell receptors. It is also important for preventing superinfection of cells by the same or different viruses utilising the same receptor, which may result in cell death. The efficient budding and release of Influenza A virus from the host cell relies on the removal of Sialic Acid residues by Neuraminidase. In contract, the HIV-1 virus gp120 envelope glycoprotein downregulates the CD4 receptor after infection of monocytes, by stimulating TNF-ÃŽÂ ± production. Other cellular mechanisms contribute to down-modulation of CD4, including the gene product Nef, which causes CD4 internalisation respectively. The precursor of gp120 and gp41, gp160, has also been found to bind CD4 intracellularly in the presence of viral protein Vpu, resulting in retention of CD4 in the Endoplasmic Rectilium. Enveloped particles leave the infected cell inconspicuously  by budding and secretion. Nonenveloped viruses  are usually thought to undergo release through cell lysis,  but some may escape by secretory mechanisms after  budding into membrane bound compartments and then  losing their membrane (Altenburg et al., 1980). Others  may subvert cellular autophagy pathways to gain access  to exocytic organelles (Jackson et al., 2005).  (Marsh)